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You're standing there in the resting state,
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so you're watching sodium and potassium go by
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because of their normal fluxes,
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and the potential that you measure is,say -75 mV.
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Now,something happens,
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there's some disturbance in the membrane near you,
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not right where you're standing but near you there's a disturbance.
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That disturbance might be a number of events
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but what we've thought about so far is that
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there's a neurotransmitter that binds.
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Somewhere upstream of you there's a neurotransmitter that binds
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to a receptor and it creates a change in membrane potential.