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U1 is shorthand for U of x1;
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is K2 + U2.
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And that means the energy E1 to begin with, the energy at the end.
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If there is a frictional force,
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then in this integral you break it up into two parts:
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the part, say, due to a spring and the part due to friction.
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The part due to a spring will integrate to give you this.
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Then, you'll still have the part due to friction left over.
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In that case the result will look like
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Instead of being zero,
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it will be the work done by friction.
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We write it symbolically this way