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The detective genre is present in Crying of Lot 49.
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That's something that you can think about productively when you
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think about Oedipa's search for knowledge and clues.
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There is a way that Pynchon is playing off that convention as well.
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To make the distinction is not to reject one for the other,
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so literary fiction and genre fiction are both part of what
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literary scholars use to make especially these kinds of
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broad-scale arguments.
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So, it's not really enough, if you want to argue about a whole
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period of literary history, to only skim off the very most
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literary works.
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Your argument doesn't have a lot of historical purchase if you do that.