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How diseases spread,
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how they can be treated or cured,
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when they kill somebody.
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The fact of the matter is,
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demon theory doesn't do a very good job of explaining disease,
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while germ theory does do a good job.
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It's the better explanation.
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So we're justified in believing in germs,
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but not demons.
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It's a matter of inference,
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not just to any old explanation,
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but inference to the best explanation.