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As tissue died,
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they gave off toxins that caused infection,
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and so infection was simply accepted
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as an inevitable, normal part of surgery.
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Lister's surgical revolution occurred with the work he published
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"On the Antiseptic principle in the Practice of Surgery",
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in 1864.
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The implications of Pasteur's work on fermentation were that
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you could have an analogy.
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If Pasteur was right, there was no spontaneous generation.
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An airborne microorganism penetrated the wound
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and caused infection or septicemia.