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was a major blow; although,
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oddly enough Harvey himself never rejected humoralism,
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Hippocrates and galen.
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Then there was the scientific revolution.
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And in particular one can think of the chemical
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revolution associated with men like Joseph Priestly and Antoine Lavoisier.
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They destroyed the Aristotelian notion of elements.
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Earth and air, for example,
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were found themselves to be composed of
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a great number of modern elements that go to make up
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what we know as the periodic table.
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And more generally,