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is to cause it to work in reverse;
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that is, to drain fluid from the bloodstream into the bowel,
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and from there it's expelled.
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So, the mechanism by which cholera kills first of all,
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and predominantly, is a sort of hemorrhaging to death,
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in which the blood serum loses its fluidly massively--
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liters can be expelled in a matter of a few hours--
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and the patient hemorrhages to death,
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in effect, losing its blood plasma and excreting
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what are called the famous rice-water stools,
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and the patient goes into hypovolemic shock.
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Nineteenth-century physicians said--