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So, Fracastoro didn't adhere to the Americanist position.
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Then there's perhaps a third more modern idea, or hypothesis,
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is that perhaps the causative agent of syphilis emerged
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in a Darwinian manner;
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the spirochete or treponema pallidum,
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arose perhaps as a mutation of some pre-existing treponemes
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that are morphologically very similar under the microscope,
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and perhaps it was--it emerged as
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an evolution from the treponeme that causes yaws.
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In any case, it was clear that whatever the site of its origin,
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it spread across Europe with terrifying rapidity.
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One can see the role of warfare, in particular,