They were intractable and would not depart.

它们难治并且不会单独存在
Next, the skin broke out with encrusted pustules.

皮肤上长了脓包
They soon grew, little by little,

脓包很快地一点点地长大
until they were the size of an acorn; which they in fact resembled.

直到如同橡子般大小事实上它们很相似
Then these ulcerated pustules ate away the skin

这些溃烂的脓包侵蚀皮肤
and sometimes infected not only the fleshy parts,

有时不仅仅感染有肉的部分
but the very bones as well.

还有骨骼
In cases where the malady was firmly established,

在一些疾病已经很顽固的病例中
in the upper parts of the body,

身体的上面部分
the patient suffered from pernicious catarrh that eroded the palate,

病人经受恶性粘膜炎恶性粘膜炎腐蚀
or the pharynx and tonsils.

下颚或者喉咽或者扁桃体
In some cases the lips, the nose and eyes were eaten away,

在一些病例中侵蚀了嘴唇鼻子和眼睛