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it would appear as one large segment instead of a large one and a smaller one.
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The absence of this smaller region tells
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you that this sample came from a sickle patient.
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You can imagine other ways of doing this,
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or ways of doing this same thing in different ways.
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It takes advantage of the specificity of the restriction enzymes,
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the fact that we know what the gene sequence that we're looking for,
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and using this technological process of electrophoresis to
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identify changes that we predict.
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Yeah, this is just one particular example of how to do it,
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but you could -
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so you have to identify something