-
or the search for work, failed harvests.
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And these newcomers, in large numbers,
-
to use contemporary medical jargon,
-
were immunologically naive.
-
That is, they were susceptible
-
and added to the pool of susceptibles in urban centers.
-
In every generation or so, urban centers,
-
whose children had already suffered smallpox
-
as an endemic childhood disease,
-
suffered major epidemics among
-
not only children but young adults,
-
adolescents and older people.