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Smallpox was both endemic year in and year out in Europe,
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and it was also epidemic sporadically
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every generation or so.
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It thrived in crowded urban environments,
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with throngs of people, and poorly vented houses and workshops.
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Now, in the eighteenth century, statistics are elusive.
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But smallpox is commonly thought--
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and this is just a guesstimate--
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to have caused perhaps a tenth of all deaths in the century in Europe,
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and a third of all deaths among children under ten-years-of-age.
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Half the population of the continent
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is estimated to have been scarred or disfigured by this disease.