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very simple observations.
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The first was that
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smallpox was clearly contagious.
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The second was that those who had recovered from the disease--
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and it was easy to know who had suffered from it because they
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were scarred and pockmarked, or also they were often blind--
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and it was a simple observation that they never
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caught smallpox a second time.
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So, the idea developed that it might be a wise measure to
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induce a mild case of smallpox artificially,
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to protect a person, or especially a child,
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from the risk of acquiring a naturally occurring but severe