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But there were problems with Jenner's method,
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and it was to require a series of subsequent improvements to
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make vaccination a fully successful procedure.
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The problems involved such things as he required,
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at the time, an arm-to-arm method,
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and this entailed the risk of spreading other diseases,
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in particular syphilis, while trying to present smallpox.
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There were also failed vaccinations that led to complications,
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and Jenner made a crucial mistake.
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He made it an article of dogmatic faith that the immunity
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derived from smallpox vaccination artificially was
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life-long, just like the natural immunity