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Why the lag phase at the beginning?
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Well, because it takes some time for
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these cellular events that I mentioned earlier to happen.
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The antigen has to be presented to helper T-cells,
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those helper T-cells have to stimulate
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a B-cell population to both proliferate and differentiate.
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So, this is a picture I showed you before.
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You can imagine that
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even when this immature B-cell gets the signal now is the time,
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you need to turn on antibody production,
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that it takes some time for it to both proliferate to make enough cells
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and for those cells