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Well, this is an approach
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that's been used in a variety of vaccines,
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most successfully with Hepatitis B,
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so the problem is where do you get these proteins?
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Well, one way to get proteins,
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and it was first used in Hepatitis B,
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is to find patients,
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find individuals who are already infected with Hepatitis B.
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So, Hepatitis is already infecting cells of their liver,
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their liver is actively making new virus.
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It turns out in the case of Hepatitis B,
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the way the lifecycle proceeds--