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This was an early example of recombinant DNA technology
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being translated into a clinical product
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and that's the vaccine that's widely used in practice now.
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Another approach which is still investigational,
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in that it's being tried for many diseases
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but not yet clinically used in any particular one,
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is maybe you don't need to introduce a whole virus
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or pieces of a protein at all.
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What if you took,
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instead of using--instead of going through the step of
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isolating the gene for Hepatitis B,
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cloning that into a plasmid,