One is in terms of how you deliver the molecule so

其一是如何精确输送这种分子
it goes where you want it to go and not where else you want it to go.

到你想要的部位
And that's an engineering problem

这的确是一个工程学问题
that we're going to talk a lot about,

我们马上就来讨论
how to deliver drugs so that you get the action that you want,

如何把药物注射到你想要它起作用的部位
at the site that you want and not the toxicity.

而不产生毒性
If you delivered Botox all over your body

如果你把肉毒杆菌素注射到全身
that wouldn't be a good thing,

这可不是个好事情
it might not even be a good

即使仅注射到身体的某一部位
thing if you delivered it one place in your body,

也不见得有多好
but it's definitely not good if you deliver it everywhere.

不过全身注射会更糟糕
So controlling the dose is really important

控制药物剂量非常重要