would function as a totally natural artificial pancreas.

与健康个体的胰腺细胞相同的作用
Now why isn't that done?

但是为什么至今此假设还没有实现
Why doesn't that already work, do you think?

你们认为是什么原因导致这个无法实现呢
What are the engineering

要想实现这项技术
problems to overcome to get that to work?

我们要先攻克什么工程难题
The same problem is with organ transplantation is that

和器官移植中的问题一样
the recipient has to be matched to the donor

受体需要与供体匹配
and so that's a problem.

这就是问题所在
That's a big problem

并且至关重要
and so can you protect these cells that you give to the recipient

那么你们想办法保护这些植入受体的细胞
from attack by the recipient's immune system?

使它们免受免疫系统的排异反应么
That's one challenge

该问题一直很具挑战性