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when a liquid meets a solid is so high
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that fluid at the surface doesn't really move at all.
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For low rates, fluid that's right at the surface doesn't move at all,
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and so roughness doesn't matter when you have no flow there.
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As the flow rate increases then roughness becomes more important.
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Two things about it in our vascular systems,
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the flow rates are generally low enough
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that you don't have worry about that.
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Our vessels are all really very similar
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in terms of their microscopic geometry,
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and that all of the blood vessels are covered
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with a monolayer of cells called endothelial cells